Design and engineering of nanoparticles and their applications to advanced nanocomposites, drug delivery system and e-display

Jian-Feng Chen, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China


28 October 2010 at 14:00

Location: JHE 326B

Nanoparticles are the essential building blocks for nanocompities, nanosytems and nano-devices, as well as for advanced drug delivery, etc. Although there were many methods developed for syntheses of nanoparticles, however, the nanoparticles engineering technology with structure tailed and particles size controlled as well as with reproducible capability is still in the challenge demand to the nanotechnology. In this talk, the engineering fundamentals, e.g, the micromixing, the nucleation and crystal growth and their interactions to influence the nanoparticles quality (PSD and Morphology) and the process scale-up were discussed, and the reactor design conception theory were proposed. Based on it, the high gravity controlled precipitation technology (HGCP) was developed to produce controllable nanoparticles with massive production at low cost. Examples of using HGCP technology to produce various inorganic nanoparticles (such as CaCO3, BaTiO3, Mg(OH)2, etc.) for advanced nanocomposites, hydrophobic drug nanoparticles (anti-cancer drug, salbutamol sulfate, cefuroxime axetil and cephradine, etc.) for enhanced drug bioavailability delivery system design and applications, as well as highly stable and transparent monodispersed nanoparticles dispersions (such as Cu nanopartilces oil dispersion, nano CaCO3 - petroleum calcium sulfonate dispersion, ZnO, TiO2, CeO2, etc.) for various functional applications were illustrated and reviewed. Some of them are now commercially produced with the largest capacity of 10,000t/a.

The applications of inorganic nanopartilces (such as Nano-CaCO3 , ZnO) in making polymer based nanocomposites (PP, PE, PVC, SBS, ABS, etc.) via our firstly invented master batch dispersion technology were also presented with the significantly improved mechanical properties and optical properties such as UV cutting. Commercial product examples such as window profiles, car bumper, glass window energy-saving film were given and discussed.
Finally, the application of nanoparticles in E-display, for example, in the E-book was interpreted and the future development for color E-display was forecasted.
In conclusions, design and massive production of Nanoparticles with tailed function will play a key role in the Nanotechnology, especially in area of advanced nanocomposites, drug delivery system and E-display.


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