Application of multi-objective optimization in the design of simulated moving bed systems

Dr. Ajay K. Ray, Professor and Graduate Chair, Department of Chemical and Biochemical Engineering University of Western Ontario, London.

12 March 2009 at 10:30

Location: JHE 326H

Simulated Moving Bed (SMB) systems are used for separations that are either impossible or difficult using traditional separation techniques. By virtue of its superior separating power, SMB has become one of the most popular techniques finding its application in petrochemical and sugar industries, and of late, there has been a drastically increased interest in SMB in pharmaceutical industry for enantio-separations. SMB systems can also be integrated to include reactions, which can provide economic benefit for equilibrium limited reversible reactions, such as many hydrogenation, isomerization, and esterification reactions. These are continuous flow reactors in which chemical reactions are carried out in the presence of solid adsorbents so that both separation by adsorption and chemical reaction are integrated into a single process unit. In-situ separation of the products facilitates the reversible reaction to completion beyond thermodynamic equilibrium and at the same time obtaining products of high purity. Furthermore, the integration of reactor and separator can lead to considerable savings in capital and operating costs. This talk deals with the application of multi-objective optimization in the innovative design of SMB systems for different applications.

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